A Multi-Agent System for Modelling Carbohydrate Oxidation in Cell

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Type: Article
Member Organisation: 165 Universita' di Camerino

Corradini, Flavio and Merelli, Emanuela and Vita, Marco (2005) A Multi-Agent System for Modelling Carbohydrate Oxidation in Cell. Lecture Notes in Computer Science, 3481. pp. 1265-1273.

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A cell consists of a large number of components interacting in a dynamic environment. The complexity of interaction among cell components and functions makes design of cell simulations a challenging task for biologists. We posit that the paradigm of agent-oriented software engineering (AOSE), in which complex systems are organized as autonomous software entities (agents) situated in an environment and communicating via high-level languages and protocols (ontologies), may be a natural approach for such models. To evaluate this approach, we constructed a model of cell components involved in the metabolic pathway of carbohydrate oxidation. The agent-oriented organization proved natural and useful in representing three different views of the cell system (functional, dynamic, and static structural) and in supporting bioscientists querying a system very close to their mental model.

Deposited by Dr Emanuela Merelli on 22 May 2005

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